The COVID-19 pandemic in Benin is part of the ongoing worldwide pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus was confirmed to have reached Benin in March 2020.

On 12 January 2020, the World Health Organization (WHO) confirmed that a novel coronavirus was the cause of a respiratory illness in a cluster of people in Wuhan City, Hubei Province, China, which was reported to the WHO on 31 December 2019.

The case fatality ratio for COVID-19 has been much lower than SARS of 2003, but the transmission has been significantly greater, with a significant total death toll. Model-based simulations for Benin suggest that the 95% confidence interval for the time-varying reproduction number R t exceeds 1.0 and has been rising since November 2020.

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On 16 March, the first COVID-19 case in the country was confirmed in Porto-Novo, the capital of Benin. Three days later, the second confirmed case was reported. The city has suspended various international flights and people coming into the country via air are being kept under 14 days' mandatory isolation. Moreover, people in Benin are advised to wear masks and go outside home only if required.